Preferred Label : Ceftobiprole Medocaril Sodium;
NCIt synonyms : 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic Acid, 7-(((2Z)-(5-amino-1,2,4-thiadiazol-3-yl)
(hydroxyimino)acetyl)amino)-3-((E)-((3'R)-1'-(((5-methyl-2-oxo-1,3-dioxol-4-yl)methoxy)carbonyl)-2-oxo(1,3'-bipyrrolidin)-3-ylidene)methyl)-8-oxo-,
Monosodium Salt, (6R,7R)-; Ceftobiprole Medocaril;
NCIt definition : The sodim salt form of ceftobiprole medocaril, a water-soluble prodrug of ceftobiprole,
a pyrrolidinone cephalosporin antibiotic, with bactericidal activity. Ceftobiprole
binds to and inactivates penicillin-binding proteins (PBPs), enzymes involved in the
terminal stages of bacterial cell wall assembly and cell wall reshaping during bacterial
growth and division. This agent exhibits a broad spectrum of activity against gram-negative
and gram-positive pathogens including methicillin-resistant S. aureus (MRSA), vancomycin-intermediate
S. aureus (VISA) and vancomycin-resistant S. aureus (VRSA). Ceftobiprole is refractory
to hydrolysis by class A and class C lactamases.;
UNII : N99027V28J;
InChIKey : MFAWUGGPPMTWPU-LCJFHXTKSA-M;
CAS number : 252188-71-9;
Molecule name : BAL5788; JNJ30982081; RO 65-5788;
Chemical formula : C26H25N8O11S2.Na;
Origin ID : C70597;
UMLS CUI : C1622308;
Currated CISMeF NLP mapping
- Manual NTBT mappings (CISMeF)
- Semantic type(s)
- UMLS correspondences (same concept)
- Validated automatic mappings to BTNT
- concept_is_in_subset
