Preferred Label : Ceftobiprole Medocaril;
NCIt synonyms : 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic Acid, 7-(((2Z)-(5-amino-1,2,4-thiadiazol-3-yl)
(hydroxyimino)acetyl)amino)-3-((E)-((3'R)-1'-(((5-methyl-2-oxo-1,3-dioxol-4-yl)methoxy)carbonyl)-2-oxo(1,3'-bipyrrolidin)-3-ylidene)methyl)-8-oxo-,
Monosodium Salt, (6R,7R)-; Ceftobiprole Medocaril Sodium;
NCIt definition : A water-soluble prodrug of ceftobiprole, a pyrrolidinone cephalosporin antibiotic,
with bactericidal activity. Ceftobiprole binds to and inactivates penicillin-binding
proteins (PBPs), enzymes involved in the terminal stages of bacterial cell wall assembly
and cell wall reshaping during bacterial growth and division. This agent exhibits
a broad spectrum of activity against gram-negative and gram-positive pathogens including
methicillin-resistant S. aureus (MRSA), vancomycin-intermediate S. aureus (VISA) and
vancomycin-resistant S. aureus (VRSA). Ceftobiprole is refractory to hydrolysis by
class A and class C lactamases.;
UNII : N99027V28J;
InChIKey : MFAWUGGPPMTWPU-LCJFHXTKSA-M;
CAS number : 252188-71-9; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 252188-71-9
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G-SRS /a ;
Molecule name : BAL5788; JNJ30982081; RO 65-5788;
Chemical formula : C26H25N8O11S2.Na;
Origin ID : C70597;
UMLS CUI : C1622308;
Automatic exact mappings (from CISMeF team)
- Currated CISMeF NLP mapping
- Manual NTBT mappings (CISMeF)
- Semantic type(s)
- UMLS correspondences (same concept)
- Validated automatic mappings to BTNT
- concept_is_in_subset
