" /> Norethindrone Acetate - CISMeF





Preferred Label : Norethindrone Acetate;

NCIt synonyms : Norethisterone Acetate; Norethindrone;

NCIt related terms : Nor-Q.D.;

NCIt definition : The orally bioavailable acetate salt of norethindrone, a synthetic progestin with some anabolic, estrogenic, and androgenic activities. As do all progestins, norethindrone binds to and activates nuclear progesterone receptors (PRs) in target tissues such as the pituitary and reproductive system; ligand-receptor complexes are translocated to the nucleus where they bind to progesterone response elements (PREs) located on target genes, followed by various transcriptional events and histone acetylation. Physiological effects include the inhibition of luteinizing hormone (LH) release, an increase in the endometrial luteal-phase, and alterations in endocervical mucus secretion.;

UNII : 9S44LIC7OJ;

InChIKey : IMONTRJLAWHYGT-ZCPXKWAGSA-N;

CAS number : 51-98-9;

Drug name : Ortho Micronor; Norlutate; Aygestin; Nor-Q.D.;

Chemical formula : C22H28O3;

NSC code : 9564;

Codes from synonyms : NSC0022844; NSC0009564;

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Keyword's position in hierarchy(ies) : arborescence

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31/05/2025


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