Central Nervous System Germinoma

Preferred Label : Central Nervous System Germinoma;

NCIt synonyms : Germinoma of Central Nervous System; Germinoma of the CNS; Germinoma of the Central Nervous System;

NCIt related terms : Germinoma; Germinoma of CNS;

NCIt definition : A malignant germ cell tumor arising from the central nervous system. It is composed of uniform cells resembling primitive germ cells. These cells have large, vesicular nuclei, prominent nucleoli and a clear, glycogen-rich cytoplasm. Additional features are lymphoid or lymphoplasmacytic infiltrates and, less frequently, scattered syncytiotrophoblastic giant cells. (Adapted from WHO);

Alternative definition : NICHD: A germinomatous germ cell tumor arising in the central nervous system; it is histologically identical to the dysgerminoma and seminoma.;

Neoplastic status : Malignant;

ICD-O code : 9064/3;

Codes from synonyms : 10065852;

Details

Origin ID

C7009;

UMLS CUI

C1333813;

Currated CISMeF NLP mapping
- CNS germinoma [MedDRA Preferred Term]
- Germinoma of central nervous system (disorder) [SNOMED CT concept]
- Germinoma of the central nervous system [ICD-11 More detail]
- Germinoma of the central nervous system [ORDO Disease]
- central nervous system germinoma [DO Concept]
DO Cross reference
- central nervous system germinoma [DO Concept]
Disease excludes abnormal cell
- Neoplastic Sex Cord-Stromal Cell [NCIt concept]
Excludes anatomical site(s)
- Gonad [NCIt concept]
Has associated anatomic sites
- Central Nervous System [NCIt concept]
- Nervous System [NCIt concept]
See also inter- (CISMeF)
- Extragonadal germinoma [ORDO Disease]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- CNS germinoma [MedDRA Preferred Term]
- Germinoma of central nervous system (disorder) [SNOMED CT concept]
- Germinoma of the central nervous system [ORDO Disease]
- central nervous system germinoma [DO Concept]
Validated automatic mappings to NTBT
- germinoma [MeSH Descriptor]
concept_is_in_subset
- CPTAC Codelists Terminology [NCIt concept]
- CPTAC Neoplasms Codelist [NCIt concept]
- CPTAC Terminology [NCIt concept]
- CTRP Disease Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- CTS-API Disease Main Type Terminology [NCIt concept]
- Clinical Trials Search-Application Programming Interface Disease Category Terminology [NCIt concept]
- GCT Authorized Value Terminology [NCIt concept]
- GCT Histology Table [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- Mapped ICDO3.1 Morphology PT Terminology [NCIt concept]
- Mapped ICDO3.1 Morphology Terminology [NCIt concept]
- Mapped ICDO3.1 Terminology [NCIt concept]
- Mapped ICDO3.2 Morphology PT Terminology [NCIt concept]
- Mapped ICDO3.2 Morphology Terminology [NCIt concept]
- Mapped ICDO3.2 Terminology [NCIt concept]
- NCI CTEP SDC Germ Cell Tumors of the CNS Sub-Category Terminology [NCIt concept]
- NCI CTEP Simplified Disease Classification Terminology [NCIt concept]
- NCIt Neoplasm Core Terminology [NCIt concept]
- NICHD Terminology [NCIt concept]
- Pediatric Endocrinology Terminology [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Indolent Clinical Course [NCIt concept]
disease_has_abnormal_cell
- Malignant Cell [NCIt concept]
- Malignant Large Germ Cell with Abundant Cytoplasm [NCIt concept]
- Malignant Primitive Germ Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Germ Cell [NCIt concept]
disease_has_finding
- Lymphoplasmacytic Infiltrate [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
- Malignant Germinomatous Cells Present [NCIt concept]
disease_has_normal_cell_origin
- Germ Cell [NCIt concept]
disease_has_normal_tissue_origin
- Germinal Layer [NCIt concept]
disease_has_primary_anatomic_site
- Central Nervous System [NCIt concept]
disease_may_have_abnormal_cell
- Malignant Syncytiotrophoblastic Giant Cell [NCIt concept]
neoplasm_has_special_category
- Solid Neoplasm [NCIt concept]

Keyword's position in hierarchy(ies) :

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