Anaplastic Kidney Wilms Tumor

Preferred Label : Anaplastic Kidney Wilms Tumor;

NCIt synonyms : Anaplastic Renal Wilm's Tumor; Anaplastic Renal Wilms' Tumor; Anaplastic Renal Wilms Tumor; Anaplastic Wilms Tumor;

NCIt definition : Wilms tumor of the kidney characterized by the presence of nuclear anaplasia. Anaplasia is defined by the presence of all of the following: multipolar polyploid mitotic figures, marked nuclear enlargement, and hyperchromasia. When anaplasia is diffuse, it is associated with an unfavorable clinical outcome.;

Neoplastic status : Malignant;

Details

Origin ID

C6952;

UMLS CUI

C1332289;

Disease excludes abnormal cell
- Neoplastic Glial Cell [NCIt concept]
Disease excludes normal cell origin
- Glial Cell [NCIt concept]
Disease may have findings
- Abdominal Mass [NCIt concept]
- Abdominal Pain [NCIt concept]
- Hematuria [NCIt concept]
- Hypertension [NCIt concept]
Has associated anatomic sites
- Genitourinary System [NCIt concept]
- Kidney [NCIt concept]
- Kidney and Ureter [NCIt concept]
- Urinary System [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
concept_is_in_subset
- NCIt Neoplasm Core Terminology [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
disease_excludes_molecular_abnormality
- DICER1 Gene Mutation [NCIt concept]
disease_excludes_normal_tissue_origin
- Germinal Layer [NCIt concept]
disease_has_abnormal_cell
- Malignant Blastemal Cell [NCIt concept]
- Malignant Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
disease_has_finding
- Anaplastic Lesion [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
- Mixed Cellular Population [NCIt concept]
- Well-Circumscribed Lesion [NCIt concept]
disease_has_normal_cell_origin
- Blastemal Cell [NCIt concept]
- Cell [NCIt concept]
- Embryonic Cell [NCIt concept]
- Nephrogenic Blastemal Cell [NCIt concept]
disease_has_normal_tissue_origin
- Embryonic Tissue [NCIt concept]
- Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Kidney [NCIt concept]
disease_mapped_to_chromosome
- Human Chromosome 11 [NCIt concept]
disease_mapped_to_gene
- WT1 Gene [NCIt concept]
disease_may_have_molecular_abnormality
- Inactivating WT1 Gene Mutation [NCIt concept]

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