Langerhans Cell Sarcoma

Preferred Label : Langerhans Cell Sarcoma;

NCIt definition : A neoplastic proliferation of Langerhans cells with overtly malignant cytologic features. It can be considered a higher grade variant of Langerhans cell histiocytosis (LCH) and it can present de novo or progress from antecedent LCH. (WHO, 2001);

Neoplastic status : Malignant;

ICD-O code : 9756/3;

Details

Origin ID

C6921;

UMLS CUI

C1260327;

Automatic exact mappings (from CISMeF team)
- Sarcoma of dendritic cells (accessory cells) [ICD-10 Sub-category]
Currated CISMeF NLP mapping
- Langerhans cell sarcoma [ICD-O code]
- Langerhans cell sarcoma [Disease (Nov.)]
- Langerhans cell sarcoma [DO Concept]
- Langerhans cell sarcoma [ICD-11 Extension code]
- Langerhans cell sarcoma [ICD-11 Subcategory]
- Langerhans cell sarcoma [MedDRA Preferred Term]
- Langerhans cell sarcoma [ORDO Disease]
- Langerhans cell sarcoma (disorder) [SNOMED CT concept]
- Langerhans cell sarcoma (morphologic abnormality) [SNOMED CT concept]
- langerhans cell sarcoma [MeSH Descriptor]
- langerhans cell sarcoma [MeSH concept]
DO Cross reference
- Langerhans cell sarcoma [DO Concept]
Disease excludes normal cell origin
- Epithelial Cell [NCIt concept]
Disease may have findings
- Aggressive Clinical Course [NCIt concept]
- CD68-Positive Neoplastic Cells Present [NCIt concept]
- Sinusoidal Infiltration [NCIt concept]
Has associated anatomic sites
- Connective and Soft Tissue [NCIt concept]
- Hematopoietic and Lymphatic System [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- Langerhans cell sarcoma [ORDO Disease]
- Langerhans cell sarcoma [DO Concept]
- Langerhans cell sarcoma [ICD-O code]
- Langerhans cell sarcoma [Disease (Nov.)]
- Langerhans cell sarcoma [MedDRA Preferred Term]
- Langerhans cell sarcoma (disorder) [SNOMED CT concept]
- Langerhans cell sarcoma (morphologic abnormality) [SNOMED CT concept]
- langerhans cell sarcoma [MeSH concept]
- langerhans cell sarcoma [MeSH Descriptor]
concept_is_in_subset
- CPTAC Codelists Terminology [NCIt concept]
- CPTAC Neoplasms Codelist [NCIt concept]
- CPTAC Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- Mapped ICDO3.1 Morphology PT Terminology [NCIt concept]
- Mapped ICDO3.1 Morphology Terminology [NCIt concept]
- Mapped ICDO3.1 Terminology [NCIt concept]
- Mapped ICDO3.2 Morphology PT Terminology [NCIt concept]
- Mapped ICDO3.2 Morphology Terminology [NCIt concept]
- Mapped ICDO3.2 Terminology [NCIt concept]
- NCIt Neoplasm Core Terminology [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- CD21-Positive Neoplastic Cells Present [NCIt concept]
- CD30-Positive Neoplastic Cells Present [NCIt concept]
- CD35-Positive Neoplastic Cells Present [NCIt concept]
- HMB-45-Positive Neoplastic Cells Present [NCIt concept]
- Indolent Clinical Course [NCIt concept]
- Intermediate Filaments Present [NCIt concept]
- Intracytoplasmic Eosinophilic Inclusion [NCIt concept]
- Polymorphic Cellular Infiltrate [NCIt concept]
disease_excludes_molecular_abnormality
- Clonal Immunoglobulin Gene Rearrangement [NCIt concept]
- Clonal T-Cell Receptor Gene Rearrangement [NCIt concept]
disease_excludes_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
disease_has_abnormal_cell
- Malignant Cell [NCIt concept]
- Malignant Langerhans Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Hematopoietic and Lymphoid Cell [NCIt concept]
- Neoplastic Histiocytic and Dendritic Cell [NCIt concept]
- Neoplastic Langerhans Cell [NCIt concept]
disease_has_finding
- Birbeck Granules Present [NCIt concept]
- CD1a-Positive Neoplastic Cells Present [NCIt concept]
- High Grade Lesion [NCIt concept]
- High Mitotic Activity [NCIt concept]
- Histiocytosis [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
- Rare Lesion [NCIt concept]
- S-100-Positive Neoplastic Cells Present [NCIt concept]
- Systemic Disease [NCIt concept]
disease_has_normal_cell_origin
- Hematopoietic and Lymphoid Cell [NCIt concept]
- Histiocyte [NCIt concept]
- Histiocytic and Dendritic Cell [NCIt concept]
- Langerhans Cell [NCIt concept]
disease_has_normal_tissue_origin
- Connective and Soft Tissue [NCIt concept]
- Hematopoietic and Lymphoid Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Hematopoietic and Lymphatic System [NCIt concept]
disease_may_have_molecular_abnormality
- BRAF Gene Mutation [NCIt concept]

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