Anaplastic Lymphoma

Preferred Label : Anaplastic Lymphoma;

NCIt synonyms : Anaplastic Large B-Cell Lymphoma;

NCIt definition : A diffuse large B-cell lymphoma variant characterized by the presence of large round, oval, or polygonal cells with bizarre pleomorphic nuclei resembling Hodgkin or Reed-Sternberg cells. It is unrelated to anaplastic large cell lymphoma which is a T-cell non-Hodgkin lymphoma.;

Neoplastic status : Malignant;

Details

Origin ID

C6916;

UMLS CUI

C1321546;

Automatic exact mappings (from CISMeF team)
- Anaplastic large B-cell lymphoma [ICD-11 More detail]
- Malignant lymphoma, large B-cell, diffuse, no International Classification of Diseases for Oncology subtype (morphologic abnormality) [SNOMED CT concept]
Currated CISMeF NLP mapping
- B-large cell anaplastic Lymphoma (Kiel Classification) [MedDRA LLT]
Disease excludes abnormal cell
- Neoplastic T-Lymphocyte and Neoplastic Natural Killer Cell [NCIt concept]
- Plasmablastic Immunoblast [NCIt concept]
- Reed-Sternberg Cell [NCIt concept]
Disease excludes normal cell origin
- Myeloid Cell [NCIt concept]
- Plasma Cell [NCIt concept]
- Precursor B-Lymphoblast [NCIt concept]
- Thymic B-Lymphocyte [NCIt concept]
Disease may have findings
- CD30-Positive Neoplastic Cells Present [NCIt concept]
- Lymphadenopathy [NCIt concept]
Excludes anatomical site(s)
- Thymus Gland [NCIt concept]
- Vascular System [NCIt concept]
Has associated anatomic sites
- Hematopoietic and Lymphatic System [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
Validated automatic mappings to BTNT
- anaplastic large B cell lymphoma [Disease (Nov.)]
concept_is_in_subset
- GDC Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCIt Neoplasm Core Terminology [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Histiocytosis [NCIt concept]
disease_excludes_molecular_abnormality
- ALK Kinase Overexpression [NCIt concept]
disease_has_abnormal_cell
- Abnormal Lymphocyte [NCIt concept]
- Anaplastic Large B-Lymphocyte [NCIt concept]
- Malignant Cell [NCIt concept]
- Neoplastic B-Lymphocyte [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Hematopoietic and Lymphoid Cell [NCIt concept]
- Neoplastic Large B-Lymphocyte [NCIt concept]
- Neoplastic Lymphocyte [NCIt concept]
disease_has_finding
- Diffuse Pattern [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
- Not Otherwise Specified Lesion [NCIt concept]
disease_has_molecular_abnormality
- Clonal Immunoglobulin Gene Rearrangement [NCIt concept]
- Clonal Immunoglobulin Kappa Light Chain Gene Rearrangement [NCIt concept]
disease_has_normal_cell_origin
- B-Lymphocyte [NCIt concept]
- Hematopoietic and Lymphoid Cell [NCIt concept]
- Lymphocyte [NCIt concept]
- Mature B-Lymphocyte [NCIt concept]
disease_has_normal_tissue_origin
- Hematopoietic and Lymphoid Tissue [NCIt concept]
- Lymphoid Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Hematopoietic and Lymphatic System [NCIt concept]
- Lymphatic System [NCIt concept]
disease_may_have_abnormal_cell
- Reed-Sternberg-Like Cell [NCIt concept]
disease_may_have_cytogenetic_abnormality
- t(14;18)(q32;q21) [NCIt concept]
- t(3;14)(q27;q32) [NCIt concept]
disease_may_have_molecular_abnormality
- Clonal BCL2 Gene Rearrangement [NCIt concept]
- Clonal BCL6 Gene Rearrangement [NCIt concept]
- Clonal Immunoglobulin Heavy Chain Gene Rearrangement [NCIt concept]
- Clonal Immunoglobulin Lambda Light Chain Gene Rearrangement [NCIt concept]

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