Preferred Label : D-methionine Formulation MRX-1024;
NCIt related terms : METHIONINE, D-;
NCIt definition : A proprietary oral formulation of D-methionine with antioxidant and antimucositis
activities. D-methionine formulation MRX-1024 may selectively protect the oral mucosa
from the toxic effects of chemotherapy and radiation therapy without compromising
antitumor activity. D-methionine may be converted into the L- isomer in vivo, particularly
in instances of L-methionine deprivation; both isomers have antioxidant activity which
may be due, in part, to their sulfur moieties and chelating properties. L-methionine,
an essential amino acid, also may help to maintain the ratio of reduced glutathione
to oxidized glutathione in cells undergoing oxidative stress and may provide a source
of L-cysteine for glutathione synthesis.;
UNII : 868496F25R;
CAS number : 348-67-4;
Molecule name : MRX-1024;
NCI Metathesaurus CUI : CL371849;
Origin ID : C69140;
UMLS CUI : C2348034;
Semantic type(s)
- concept_is_in_subset
