Iodine I-123 Iodometomidate

Preferred Label : Iodine I-123 Iodometomidate;

NCIt synonyms : I-123-IMTO; Iodine I 123 Iodometomidate;

NCIt definition : An iodine I-123 conjugate of metomidate (MTO) with potential application in adrenal imaging. Metomidate is a potent and selective inhibitor of the cytochrome P-450 enzymes, especially CYP11B1 (11 beta-hydroxylase) and CYP11B2 (aldosterone synthase). Because both CYP11B1 and CYP11B2 are expressed exclusively in the adrenal cortex, I-123 iodometomidate can be used as a radiotracer for adrenal scintigraphy.;

NCI Metathesaurus CUI : CL371853;

Details

Origin ID

C69137;

UMLS CUI

C2346582;

Semantic type(s)
- Pharmacologic Substance [UMLS semantic type]
concept_is_in_subset
- NCI Drug Dictionary Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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