" /> Pasireotide - CISMeF





Preferred Label : Pasireotide;

NCIt synonyms : Cyclo((4R)-4-(2-aminoethylcarbamoyloxy)-L-prolyl-L-phenylglycyl-D-tryptophyl-L-lysyl-4-O-benzyl-L-tyrosyl-L-phenylalanyl-);

NCIt definition : A synthetic long-acting cyclic peptide with somatostatin-like activity. Pasireotide activates a broad spectrum of somatostatin receptors, exhibiting a much higher binding affinity for somatostatin receptors 1, 3, and 5 than octreotide in vitro, as well as a comparable binding affinity for somatostatin receptor 2. This agent is more potent than somatostatin in inhibiting the release of human growth hormone (HGH), glucagon, and insulin.;

UNII : 98H1T17066;

InChIKey : VMZMNAABQBOLAK-DBILLSOUSA-N;

CAS number : 396091-73-9; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 396091-73-9 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Molecule name : SOM230;

Chemical formula : C58H66N10O9;

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15/05/2024


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