Pasireotide - CISMeF

Preferred Label : Pasireotide;

NCIt synonyms : Cyclo((4R)-4-(2-aminoethylcarbamoyloxy)-L-prolyl-L-phenylglycyl-D-tryptophyl-L-lysyl-4-O-benzyl-L-tyrosyl-L-phenylalanyl-);

NCIt definition : A synthetic long-acting cyclic peptide with somatostatin-like activity. Pasireotide activates a broad spectrum of somatostatin receptors, exhibiting a much higher binding affinity for somatostatin receptors 1, 3, and 5 than octreotide in vitro, as well as a comparable binding affinity for somatostatin receptor 2. This agent is more potent than somatostatin in inhibiting the release of human growth hormone (HGH), glucagon, and insulin.;

UNII : 98H1T17066;

InChIKey : VMZMNAABQBOLAK-DBILLSOUSA-N;

CAS number : 396091-73-9;

Molecule name : SOM230;

Chemical formula : C58H66N10O9;

Details

Origin ID

C69131;

UMLS CUI

C1872203;

CISMeF manual mappings
- Pasireotide (substance) [SNOMED CT concept]
See also inter- (CISMeF)
- Product containing pasireotide (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Pasireotide (substance) [SNOMED CT concept]
- Product containing pasireotide (medicinal product) [SNOMED CT concept]
- pasireotide [ATC Code]
- pasireotide [International Nonproprietary Name]
- pasireotide [MeSH Supplementary Concept]
- pasireotide [MeSH concept]
Validated automatic mappings to BTNT
- pasireotide [ATC Code]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
has_target
- Somatostatin Receptor [NCIt concept]

Keyword's position in hierarchy(ies) :

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