Preferred Label : BCR-ABL p210-b3a2 Breakpoint-derived Pentapeptide Vaccine;
NCIt synonyms : p210-B3A2 Derived Peptide Vaccine;
NCIt definition : A multipeptide vaccine consisting of five peptides derived from the bcr-abl p210-b3a2
breakpoint fusion protein with potential antineoplastic activity. Vaccination with
bcr-abl p210-b3a2 breakpoint-derived multipeptide vaccine may stimulate the host immune
system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells that express
the bcr-abl p210-b3a2 breakpoint fusion protein. In chronic myelogenous leukemia (CML),
fusion genes typically result from the fusion of either bcr exon b2 or exon b3 to
abl exon a2, resulting in either a b3a2 or a b2a2 gene fusion product.;
Molecule name : CML-VAX100;
NCI Metathesaurus CUI : CL371859;
Origin ID : C69082;
UMLS CUI : C2346900;
Semantic type(s)
- concept_is_in_subset
