NCIt related terms : GRANULE, EXTENDED RELEASE; Prolonged-release granules;
NCIt definition : A solid in the shape of a small particle or grain designed to release active and/or
inert ingredient(s) at a controlled, prolonged rate so as to reduce dosing frequency.;
Alternative definition : EDQM-HC: Solid preparation consisting of granules showing a slower release than that
of conventional-release granules. This deliberate modification is achieved by a special
formulation design and/or manufacturing method. Prolonged-release granules are usually
single-dose preparations intended for oral use.;