Preferred Label : Adenovirus Encoding Human Aquaporin-1;
NCIt synonyms : AdhAQP1; AAV2hAQP1;
NCIt definition : A replication-deficient, recombinant adenovirus encoding human aquaporin-1 with potential
membrane water channel activity. Upon transfection of salivary glands, adenovirus
encoding human aquaporin-1 (AdhAQP1) directs human aquaporin-1 (hAQP1) expression
in the apical and basolateral plasma membranes of salivary secretory cells, which
may result in increased saliva production. hAQP1, a water channel protein, is one
of several highly conserved water channel proteins that mediate water permeability
in cells of water-transporting tissues.;
Molecule name : AAV2 hAQP1; AAV2-hAQP1;
NCI Metathesaurus CUI : CL374275;
Origin ID : C68932;
UMLS CUI : C2347432;
Semantic type(s)
concept_is_in_subset