LSP1 wt Allele

Preferred Label : LSP1 wt Allele;

NCIt synonyms : Lymphocyte-Specific Protein 1 wt Allele; pp52; WP34;

NCIt definition : Human LSP1 wild-type allele is located in the vicinity of 11p15.5 and is approximately 39 kb in length. This allele, which encodes lymphocyte-specific protein 1, may be involved in the regulation of neutrophil motility, adhesion, and transendothelial migration.;

NCIt note : The LSP1 genes can undergo alternative splicing, which results in multiple transcript variants encoding different isoforms. A SNP has been identified in the LSP1 gene (rs3817198), which is associated with increases in breast cancer incidence. (Nature 2007; 447:1087-1093);

GenBank Accession Number : NM_002339;

PubMed : 17529967;

Details

Origin ID

C68714;

UMLS CUI

C2346628;

OMIM relation
- Lymphocyte-specific protein [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 11p15.5 [NCIt concept]
gene_plays_role_in_process
- Chemotactic Process [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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