TOX3 wt Allele

Preferred Label : TOX3 wt Allele;

NCIt synonyms : TNRC9; TOX High Mobility Group Box Family Member 3 wt Allele; CAGF9;

NCIt definition : Human TOX3 wild-type allele is located in the vicinity of 16q12.1 and is approximately 110 kb in length. This allele, which encodes TOX high mobility group box family member 3 protein, may play a role in the regulation of transcription.;

NCIt note : Two SNPs that occur in the TOX3 gene (rs12443621 and rs8051542) have been linked to increased breast cancer incidence. (Nature 2007; 447:1087-1093);

GenBank Accession Number : XM_049037;

PubMed : 17529967;

Details

Origin ID

C68711;

UMLS CUI

C2348638;

OMIM relation
- Tox high mobility group box family member 3 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 16q12.1 [NCIt concept]
gene_plays_role_in_process
- Chromatin Structural Process [NCIt concept]
- DNA Binding [NCIt concept]
- Negative Regulation of Apoptosis [NCIt concept]
- Transcriptional Activation [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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