" /> Stage IV Laryngeal Cancer AJCC v6 - CISMeF





Preferred Label : Stage IV Laryngeal Cancer AJCC v6;

NCIt synonyms : Stage IV Carcinoma of Larynx AJCC v6; Stage IV Carcinoma of the Larynx AJCC v6; Stage IV Larynx Carcinoma AJCC v6; Laryngeal Cancer, Stage IV AJCC v6; Stage IV Laryngeal Carcinoma AJCC v6;

NCIt related terms : stage IV laryngeal cancer; Stage IV Laryngeal Throat Cancer;

NCIt definition : Stage IV includes: IVA: (T4a, N0, M0); (T4a, N1, M0); (T1, N2, M0); (T2, N2, M0); (T3, N2, M0); (T4a, N2, M0); IVB: (T4b, Any N, M0); (Any T, N3, M0); IVC: (Any T, Any N, M1). T4: (Supraglottis) T4a: Tumor invades through the thyroid cartilage and/or invades tissues beyond the larynx (e.g., trachea, soft tissues of neck including deep extrinsic muscle of the tongue, strap muscles, thyroid, or esophagus). T4b: Tumor invades prevertebral space, encases carotid artery, or invades mediastinal structures. (Glottis) T4a: Tumor invades through the thyroid cartilage and/or invades tissues beyond the larynx (e.g., trachea, soft tissues of neck including deep extrinsic muscles of the tongue, strap muscles, thyroid, or esophagus). T4b: Tumor invades prevertebral space, encases carotid artery, or invades mediastinal structures. (Subglottis) T4a: Tumor invades cricoid or thyroid cartilage and/or invades tissues beyond the larynx (e.g., trachea, soft tissues of neck including deep extrinsic muscles of the tongue, strap muscles, thyroid, or esophagus). T4b: Tumor invades prevertebral space, encases carotid artery, or invades mediastinal structures. N2: Metastasis in a single ipsilateral lymph node, more than 3 cm but not more than 6 cm in greatest dimension, or in multiple ipsilateral lymph nodes, none more than 6 cm in greatest dimension, or in bilateral or contralateral lymph nodes, none more than 6 cm in greatest dimension. N2a: Metastasis in a single ipsilateral lymph node more than 3 cm but not more than 6 cm in greatest dimension. N2b: Metastasis in multiple ipsilateral lymph nodes, none more than 6 cm in greatest dimension. N2c: Metastasis in bilateral or contralateral lymph nodes, none more than 6 cm in greatest dimension. N3: Metastasis in a lymph node more than 6 cm in greatest dimension. M1: Distant metastasis. (AJCC 6th ed.);

Alternative definition : NCI-GLOSS: Stage IV is divided into stage IVA, stage IVB, and stage IVC. In stage IVA, (1) cancer has spread through the thyroid cartilage and/or has spread to tissues beyond the larynx, such as the neck, trachea, thyroid, or esophagus; cancer may have spread to one lymph node on the same side of the neck as the original tumor and the lymph node is 3 centimeters or smaller; or (2) cancer has spread to one lymph node on the same side of the neck as the original tumor and the lymph node is larger than 3 centimeters but not larger than 6 centimeters, or has spread to more than one lymph node anywhere in the neck with none larger than 6 centimeters; cancer may have spread to tissues beyond the larynx, such as the neck, trachea, thyroid, or esophagus. The vocal cords may not move normally. In stage IVB, (1) cancer has spread to the space in front of the spinal column, surrounds the carotid artery, or has spread to parts of the chest; cancer may have spread to one or more lymph nodes anywhere in the neck and the lymph nodes may be any size; or (2) cancer has spread to a lymph node that is larger than 6 centimeters and may have spread as far as the space in front of the spinal column, around the carotid artery, or to parts of the chest. The vocal cords may not move normally. In stage IVC, cancer has spread to other parts of the body, such as the lungs, liver, or bone.;

Neoplastic status : Malignant;

Codes from synonyms : CDR0000045284;

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07/05/2025


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