Cerebellar Pilocytic Astrocytoma

Preferred Label : Cerebellar Pilocytic Astrocytoma;

NCIt synonyms : Pilocytic Astrocytoma of Cerebellum; Pilocytic Astrocytoma of the Cerebellum;

NCIt definition : A WHO Grade 1 astrocytoma which arises in the cerebellum. The tumor is composed of spindle shaped cells with numerous collections of reddish astrocytic fibers called Rosenthal fibers. Over 80% or the cerebellar astrocytomas of childhood are pilocytic. Pilocytic astrocytomas may rarely occur in adults. They are usually treated by surgical resection and in most cases have a favorable prognosis.;

Neoplastic status : Undetermined;

Details

Origin ID

C6809;

UMLS CUI

C0349620;

Automatic exact mappings (from CISMeF team)
- pilocytic astrocytoma of cerebellum [DO Concept]
Currated CISMeF NLP mapping
- Pilocytic astrocytoma of cerebellum (disorder) [SNOMED CT concept]
DO Cross reference
- pilocytic astrocytoma of cerebellum [DO Concept]
Disease excludes abnormal cell
- Poorly Differentiated Neoplastic Astrocyte [NCIt concept]
Disease may have findings
- BRAF Fusion Positive [NCIt concept]
- Eosinophilic Granular Bodies Present [NCIt concept]
- Headache [NCIt concept]
- Indolent Clinical Course [NCIt concept]
- MAPK Pathway Alteration Positive [NCIt concept]
- Nausea and Vomiting [NCIt concept]
- Rosenthal Fibers Present [NCIt concept]
- Well-Circumscribed Lesion [NCIt concept]
Excludes anatomical site(s)
- Spinal Cord [NCIt concept]
Has associated anatomic sites
- Brain [NCIt concept]
- Central Nervous System [NCIt concept]
- Cerebellum [NCIt concept]
- Infratentorial Brain [NCIt concept]
- Nervous System [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- Pilocytic astrocytoma of cerebellum (disorder) [SNOMED CT concept]
- pilocytic astrocytoma of cerebellum [DO Concept]
disease_excludes_finding
- Grade 4 Lesion [NCIt concept]
- Precise Histogenesis Unknown [NCIt concept]
disease_has_abnormal_cell
- Neoplastic Astrocyte [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Glial Cell [NCIt concept]
- Neoplastic Neuroepithelial Cell [NCIt concept]
- Neoplastic Neuroepithelial Cell and Neoplastic Perineural Cell [NCIt concept]
- Neoplastic Piloid Astrocyte [NCIt concept]
- Neoplastic Protoplasmic Astrocyte [NCIt concept]
disease_has_finding
- Benign Cellular Infiltrate [NCIt concept]
- Biphasic Pattern [NCIt concept]
- Glomeruloid Vessels Present [NCIt concept]
- Hyalinized Vessels Present [NCIt concept]
- Low Cellularity Present [NCIt concept]
- Low Grade Lesion [NCIt concept]
- Microcystic Change [NCIt concept]
- Microvascular Proliferation [NCIt concept]
- Slow Growing Mass [NCIt concept]
disease_has_grade
- Grade 1 [NCIt concept]
- Low Grade [NCIt concept]
disease_has_normal_cell_origin
- Astrocyte [NCIt concept]
- Glial Cell [NCIt concept]
- Neuroepithelial Cell [NCIt concept]
- Neuron, Neuroepithelial Cell, and Supporting Cell of the Nervous System [NCIt concept]
disease_has_normal_tissue_origin
- Nerve Tissue, Neuroepithelial Tissue, and Nerve Sheaths [NCIt concept]
- Neuroepithelial Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Brain [NCIt concept]
- Central Nervous System [NCIt concept]
- Cerebellum [NCIt concept]
- Head [NCIt concept]
- Infratentorial Brain [NCIt concept]
- Nervous System [NCIt concept]
disease_may_have_abnormal_cell
- Neoplastic Oligodendrocyte-Like Cell [NCIt concept]
disease_may_have_cytogenetic_abnormality
- Gain of Chromosome 19 [NCIt concept]
- Gain of Chromosome 22 [NCIt concept]
- Gain of Chromosome 7 [NCIt concept]
- Gain of Chromosome 8 [NCIt concept]

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