Malignant Pancreatic Gastrinoma

Preferred Label : Malignant Pancreatic Gastrinoma;

NCIt synonyms : Pancreatic G-Cell Carcinoma;

NCIt definition : A gastrin-producing neuroendocrine tumor arising from the pancreas. It is characterized by inappropriate secretion of gastrin and associated with Zollinger Ellison syndrome. It displays vascular invasion and metastasizes to other anatomic sites.;

Neoplastic status : Malignant;

Details

Origin ID

C67458;

UMLS CUI

C1881585;

Disease excludes abnormal cell
- Large Osteoclastic Giant Cell [NCIt concept]
- Neoplastic Smooth Muscle Cell [NCIt concept]
Has associated anatomic sites
- Digestive System [NCIt concept]
- Pancreas [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- Malignant gastrinoma of pancreas (disorder) [SNOMED CT concept]
concept_is_in_subset
- CTRP Disease Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
disease_excludes_finding
- Absence of a Hormonal Syndrome [NCIt concept]
- High Mitotic Activity [NCIt concept]
- Low Grade Neuroendocrine Lesion [NCIt concept]
- Poorly Differentiated Neuroendocrine Lesion [NCIt concept]
- Severe Cytologic Atypia [NCIt concept]
disease_has_abnormal_cell
- Neoplastic Cell [NCIt concept]
- Neoplastic Endocrine Cell [NCIt concept]
- Neoplastic Epithelial Cell [NCIt concept]
- Neoplastic Neuroendocrine Cell [NCIt concept]
disease_has_associated_disease
- Zollinger Ellison Syndrome [NCIt concept]
disease_has_finding
- Endocrine Differentiation [NCIt concept]
- Epithelial Component Present [NCIt concept]
- Gastrin-Positive Neoplastic Cells Present [NCIt concept]
- Gyriform Trabecular Pattern [NCIt concept]
- Intermediate Grade Neuroendocrine Lesion [NCIt concept]
- Low Mitotic Activity [NCIt concept]
- Neuroendocrine Differentiation [NCIt concept]
- Presence of a Hormonal Syndrome [NCIt concept]
- Pseudorosette Formation [NCIt concept]
- Tumor Vascular Invasion [NCIt concept]
- Well Differentiated Neuroendocrine Lesion [NCIt concept]
disease_has_normal_cell_origin
- Endocrine Cell of the Digestive System [NCIt concept]
- Epithelial Cell [NCIt concept]
- Islet Cell [NCIt concept]
disease_has_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
- Islet of Langerhans [NCIt concept]
disease_has_primary_anatomic_site
- Digestive System [NCIt concept]
- Islet of Langerhans [NCIt concept]
- Pancreas [NCIt concept]
disease_mapped_to_gene
- MEN1 Gene [NCIt concept]
- VHL Gene [NCIt concept]
disease_may_have_cytogenetic_abnormality
- Loss of Chromosome 3p [NCIt concept]
- del(18q21) [NCIt concept]

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