Malignant Pancreatic Somatostatinoma

Preferred Label : Malignant Pancreatic Somatostatinoma;

NCIt synonyms : Pancreatic Malignant Somatostatinoma; Pancreatic Delta Cell Carcinoma;

NCIt definition : A neuroendocrine tumor that arises from the delta cells of the pancreas. It is characterized by inappropriate secretion of somatostatin and associated with diabetes mellitus, hypochlorhydria, gallbladder disease, diarrhea, steatorrhea, anemia, and weight loss. It displays vascular invasion and metastasizes to other anatomic sites.;

Neoplastic status : Malignant;

Details

Origin ID

C67369;

UMLS CUI

C0279727;

Disease excludes abnormal cell
- Large Osteoclastic Giant Cell [NCIt concept]
- Neoplastic Smooth Muscle Cell [NCIt concept]
Disease may have findings
- Diarrhea [NCIt concept]
- Psammoma Body Formation [NCIt concept]
- Steatorrhea [NCIt concept]
- Weight Loss [NCIt concept]
Has associated anatomic sites
- Digestive System [NCIt concept]
- Pancreas [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
concept_is_in_subset
- CTRP Disease Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
disease_excludes_finding
- Absence of a Hormonal Syndrome [NCIt concept]
- High Mitotic Activity [NCIt concept]
- Low Grade Neuroendocrine Lesion [NCIt concept]
- Poorly Differentiated Neuroendocrine Lesion [NCIt concept]
- Severe Cytologic Atypia [NCIt concept]
disease_has_abnormal_cell
- Neoplastic Cell [NCIt concept]
- Neoplastic Endocrine Cell [NCIt concept]
- Neoplastic Epithelial Cell [NCIt concept]
- Neoplastic Neuroendocrine Cell [NCIt concept]
disease_has_finding
- Endocrine Differentiation [NCIt concept]
- Epithelial Component Present [NCIt concept]
- Glandular Pattern [NCIt concept]
- Insular Pattern [NCIt concept]
- Intermediate Grade Neuroendocrine Lesion [NCIt concept]
- Low Mitotic Activity [NCIt concept]
- Neuroendocrine Differentiation [NCIt concept]
- Presence of a Hormonal Syndrome [NCIt concept]
- Somatostatin-Positive Neoplastic Cells Present [NCIt concept]
- Trabecular Pattern [NCIt concept]
- Tubular Pattern [NCIt concept]
- Tumor Vascular Invasion [NCIt concept]
- Well Differentiated Neuroendocrine Lesion [NCIt concept]
disease_has_normal_cell_origin
- Delta Cell [NCIt concept]
- Delta Cell of the Pancreas [NCIt concept]
- Endocrine Cell of the Digestive System [NCIt concept]
- Epithelial Cell [NCIt concept]
- Islet Cell [NCIt concept]
disease_has_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
- Islet of Langerhans [NCIt concept]
disease_has_primary_anatomic_site
- Digestive System [NCIt concept]
- Islet of Langerhans [NCIt concept]
- Pancreas [NCIt concept]
disease_mapped_to_gene
- MEN1 Gene [NCIt concept]
- VHL Gene [NCIt concept]
disease_may_have_associated_disease
- Anemia [NCIt concept]
- Diabetes Mellitus [NCIt concept]
- Gallbladder Disorder [NCIt concept]

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