Preferred Label : Kunecatechins Ointment;
NCIt synonyms : Defined Green Tea Catechin Extract OIntment; Polyphenon E Ointment; Polyphenon E Topical Ointment; Kunecatechin Ointment;
NCIt definition : A topical ointment containing a green tea polyphenol mixture (kunecatechins) with
potential antiviral, antibacterial, antioxidant, and chemopreventive activities. Kunecatechins
is a partially purified fraction of the aqueous extract of green tea leaves from Camellia
sinensis and contains catechins and other green tea components. Catechins, polyphenolic
antioxidant plant metabolites or flavonoids, comprise most of the drug substance in
kunecatechins with epigallocatechin gallate (EGCG) present as the primary catechin.
Catechins may inhibit basic functions of human papillomavirus (HPV), counteract specific
changes in tumor cells, affect cell signaling, and stimulate the immune system. Topical
application of kunecatechins ointment has been reported to reduce HPV-induced genital
and anal warts through a not yet fully understood mechanism, which may involve anti-oxidative
activity.;
Drug name : Veregen;
Origin ID : C67049;
UMLS CUI : C0917977;
Semantic type(s)
- concept_is_in_subset
