Tocophersolan - CISMeF

Preferred Label : Tocophersolan;

NCIt synonyms : Vitamin E PEG-1000-Succinate; d-Alpha Tocopheryl Polyethylene Glycol 1000 Succinate; TPGS; Tocofersolan; Vitamin E Polyethylene Glycol 1000 Succinate; Vitamin E Polyethylene Glycol Succinate;

NCIt definition : A water-soluble amphipathic formulation of d-alpha-tocopherol succinate coupled, through a succinate linker, to polyethylene glycol (PEG) 1000. Due to its amphipathic property in which it forms its own micelles, tocophersolan is easily taken up into enterocytes, even in the absence of bile salts; fat soluble d-alpha-tocopherol is then released after hydrolysis. This formulation enhances the absorption of d-alpha-tocopherol compared to the administration of free d-alpha-tocopherol. In addition, tocophersolan may enhance the absorption of water-insoluble agents and other fat-soluble vitamins.;

UNII : O03S90U1F2;

CAS number : 9002-96-4;

Chemical formula : C33H54O5(C2H4O)n;

Details

Origin ID

C67044;

UMLS CUI

C0606070;

Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
- Vitamin [UMLS semantic type]
UMLS correspondences (same concept)
- tocofersolan [ATC Code]
- tocophersolan [MeSH concept]
- tocophersolan [MeSH Supplementary Concept]
Validated automatic mappings to BTNT
- tocofersolan [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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