Preferred Label : Anti-IL-13 Humanized Monoclonal Antibody TNX-650;
Obsolete resource : true;
NCIt synonyms : Monoclonal Antibody TNX-650; TNX-650;
NCIt definition : A humanized monoclonal antibody directed against interleukin-13 (IL-13) with potential
antineoplastic activity. Anti-IL-13 humanized monoclonal antibody TNX-650 binds to
and blocks the activity of IL-13, which may result in the inhibition of Hodgkin lymphoma
cell proliferation. IL-13 cytokine, an important mediator in allergic inflammation,
may be an autocrine growth factor for Hodgkin lymphoma cells.;
NCIt note : See 'Lebrikizumab(C87767)';
Concept status : Retired_Concept;
Origin ID : C66988;
UMLS CUI : C1881890;
Currated CISMeF NLP mapping
- Semantic type(s)
