NCIt definition : An emulsion containing the tartrate salt of the semisynthetic vinca alkaloid vinorelbine
with antineoplastic activity. Vinorelbine binds to tubulin, inhibiting tubulin polymerization
into microtubules; cell division is prevented, the cell cycle is arrested metaphase
and cell death ensues. In this formulation vinorelbine is emulsified in a homogeneous
suspension of nanoparticles, which protects the venous endothelium from coming into
direct contact with the active ingredient, potentially reducing vinorelbine-associated
venous toxicity at the venous injection site.;