Preferred Label : Mopidamol;
NCIt synonyms : 2,6-Bis(diethanolamino)-4-piperidino-pyrimido[5,4-d]pyrimidine; 2,2',2,2'-[[4-(1-Piperidinyl)pyrimido[5,4-d]pyrimidine-2,6-diyl]dinitrilo]tetrakisethanol; 2,2',2,2'-[(4-Piperidinopyrimido[5,4-d-]pyrimidine-2,6-diyl)dinitrilo]tetraethanol;
NCIt definition : A derivative of dipyridamole that is a phosphodiesterase inhibitor, with potential
antiplatelet activity. Mopidamol inhibits the hydrolysis of cyclic nucleotides, such
as cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP),
by cyclic nucleotide phosphodiesterases; thus, cAMP- and cGMP-dependent processes
are potentiated. This leads to the induction of prostacyclin synthesis, the inhibition
of thromboxane B2 synthesis and prevention of platelet activation and aggregation.;
UNII : 4Q0IWP8B8O;
InChIKey : FOYWNSCCNCUEPU-UHFFFAOYSA-N;
CAS number : 13665-88-8;
Drug name : Rapenton;
Molecule name : RA-233;
Chemical formula : C19H31N7O4;
Origin ID : C668;
UMLS CUI : C0026523;
Automatic exact mappings (from CISMeF team)
Currated CISMeF NLP mapping
Semantic type(s)
UMLS correspondences (same concept)
concept_is_in_subset