Breast Atypical Medullary Carcinoma

Preferred Label : Breast Atypical Medullary Carcinoma;

NCIt synonyms : Infiltrating Ductal Breast Carcinoma with Medullary Features; Atypical Medullary Breast Carcinoma;

NCIt related terms : Atypical medullary carcinoma;

NCIt definition : An invasive ductal breast carcinoma characterized by the presence of a predominantly syncytial architectural pattern. It may have some, but not all the strictly defined additional morphologic criteria which are necessary for the diagnosis of medullary breast carcinoma (presence of a diffuse lymphoplasmacytic infiltrate, neoplastic round cells with abundant cytoplasm and vesicular nuclei, complete histological circumscription, and absence of glandular or tubular structures). It does not have the relatively favorable outcome that characterizes medullary breast carcinoma.;

Neoplastic status : Malignant;

ICD-O code : 8513/3;

Details

Origin ID

C66719;

UMLS CUI

C1879758;

Automatic exact mappings (from CISMeF team)
- Atypical medullary carcinoma [ICD-O code]
- Atypical medullary carcinoma [ICD-11 Extension code]
- Atypical medullary carcinoma (morphologic abnormality) [SNOMED CT concept]
Disease excludes abnormal cell
- Malignant Squamous Cell [NCIt concept]
- Malignant Stromal Cell [NCIt concept]
- Neoplastic Smooth Muscle Cell [NCIt concept]
- Neoplastic Squamous Cell [NCIt concept]
Disease may have findings
- Breast Lump [NCIt concept]
- Calcification [NCIt concept]
- Lymphoplasmacytic Infiltrate [NCIt concept]
- Pain [NCIt concept]
- Well-Circumscribed Lesion [NCIt concept]
Has associated anatomic sites
- Breast [NCIt concept]
See also inter- (CISMeF)
- medullary ductal breast carcinoma [Disease (Nov.)]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
concept_is_in_subset
- GDC Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- Mapped ICDO3.1 Morphology PT Terminology [NCIt concept]
- Mapped ICDO3.1 Morphology Terminology [NCIt concept]
- Mapped ICDO3.1 Terminology [NCIt concept]
- Mapped ICDO3.2 Morphology PT Terminology [NCIt concept]
- Mapped ICDO3.2 Morphology Terminology [NCIt concept]
- Mapped ICDO3.2 Terminology [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Mixed Neoplastic Glandular and Squamous Cell Population [NCIt concept]
disease_excludes_molecular_abnormality
- CDH1 Gene Inactivation [NCIt concept]
- Loss of E-cadherin Expression [NCIt concept]
disease_has_abnormal_cell
- Adenocarcinoma Cell [NCIt concept]
- Ductal Carcinoma Cell [NCIt concept]
- Malignant Cell [NCIt concept]
- Malignant Epithelial Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Epithelial Cell [NCIt concept]
- Neoplastic Glandular Cell [NCIt concept]
disease_has_finding
- Carcinomatous Component Present [NCIt concept]
- Epithelial Component Present [NCIt concept]
- Invasive Lesion [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
- Not Otherwise Specified Lesion [NCIt concept]
- Syncytial Pattern [NCIt concept]
disease_has_normal_cell_origin
- Epithelial Cell [NCIt concept]
- Terminal Ductal Lobular Unit Cell [NCIt concept]
disease_has_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
- Mammary Epithelium [NCIt concept]
- Terminal Ductal Lobular Unit [NCIt concept]
disease_has_primary_anatomic_site
- Breast [NCIt concept]
disease_mapped_to_gene
- CCND1 Gene [NCIt concept]
- ERBB2 Gene [NCIt concept]
disease_may_have_abnormal_cell
- Round Adenocarcinoma Cell with Abundant Cytoplasm and Vesicular Nucleus [NCIt concept]
disease_may_have_molecular_abnormality
- CCND1 Gene Amplification [NCIt concept]
- CCND1 Protein Overexpression [NCIt concept]
- Cyclin D1 Messenger RNA Overexpression [NCIt concept]
- ERBB2 Gene Amplification [NCIt concept]
- ERBB2 Protein Overexpression [NCIt concept]
- TP53 Gene Inactivation [NCIt concept]

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