" /> Zofenoprilat Arginine - CISMeF





Preferred Label : Zofenoprilat Arginine;

NCIt synonyms : L-Proline, 1-(3-mercapto-2-methyl-1-oxopropyl)-4-(phenylthio)-, (1(R*),2alpha,4alpha)-, compd. with L-arginine (1:1);

NCIt definition : The arginine salt of zofenoprilat, a sulfhydryl angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. Zofenoprilat competitively binds to and inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II. This prevents the potent vasoconstrictive actions of angiotensin II and results in vasodilation. Zofenoprilat also decreases angiotensin II-induced aldosterone secretion by the adrenal cortex, which leads to an increase in sodium excretion and subsequently increases water outflow.;

UNII : 36F26ZSQ0D;

InChIKey : OSKWTWSFSUAPKP-KQUFBQNASA-N;

CAS number : 81872-09-5;

Molecule name : SQ 26,703; SQ 26703;

Chemical formula : C15H19NO3S2.C6H14N4O2;

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12/12/2025


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