Zabiciprilat - CISMeF

Preferred Label : Zabiciprilat;

NCIt definition : A non-thiol angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. Zabiciprilat competitively binds to and inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II. This prevents the potent vasoconstrictive actions of angiotensin II and results in vasodilation. Zabiciprilat also decreases angiotensin II-induced aldosterone secretion by the adrenal cortex, which leads to an increase in sodium excretion and subsequently increases water outflow.;

UNII : 0A2D355316;

InChIKey : HBZJVGFXZTUXNI-XMQLQKOFSA-N;

CAS number : 90103-92-7;

Chemical formula : C21H28N2O5;

Details

Origin ID

C66678;

UMLS CUI

C0165809;

Currated CISMeF NLP mapping
- zabiciprilat [MeSH concept]
- zabiciprilat [MeSH Supplementary Concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- zabiciprilat [MeSH Supplementary Concept]
- zabiciprilat [MeSH concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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