" /> Zabiciprilat - CISMeF





Preferred Label : Zabiciprilat;

NCIt definition : A non-thiol angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. Zabiciprilat competitively binds to and inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II. This prevents the potent vasoconstrictive actions of angiotensin II and results in vasodilation. Zabiciprilat also decreases angiotensin II-induced aldosterone secretion by the adrenal cortex, which leads to an increase in sodium excretion and subsequently increases water outflow.;

UNII : 0A2D355316;

InChIKey : HBZJVGFXZTUXNI-XMQLQKOFSA-N;

CAS number : 90103-92-7;

Chemical formula : C21H28N2O5;

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28/07/2025


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