NCIt definition : An alpha-tocopherol ester of all trans-retinoic acid (ATRA or tretinoin), with skin
healing, differentiation inducing and anti-leukemia activities. By stimulating the
formation of tissue granulation and wound healing, tretinoin tocoferil promotes the
healing of skin ulcers. In addition, this agent induces the granulocytic differentiation
of human leukemia cells and inhibits cellular proliferation. Tretinoin tocoferil does
not induce teratogenesis and is less toxic than ATRA.;