Thiopental Sodium

Preferred Label : Thiopental Sodium;

NCIt synonyms : Sodium Penthiobarbital; 4,6(1H,5H)-Pyrimidinedione, 5-ethyldihydro-5-(1-methylbutyl)-2-thioxo-, Monosodium Salt;

NCIt related terms : Sodium Thiopental;

NCIt definition : The sodium salt form of thiopental, an ultrashort-acting barbituric acid derivative, with anesthetic activity. Thiopental binds to the chloride ionophore site of the gamma-aminobutyric acid (GABA)-A/chloride ionophore receptor complex, thereby enhancing the inhibitory actions of GABA-A in the brain. This leads to synaptic inhibition, decreased neuronal excitability and induction of anesthesia. In addition, this agent decreases glutamate (Glu) responses.;

UNII : 49Y44QZL70;

InChIKey : AWLILQARPMWUHA-UHFFFAOYSA-M;

CAS number : 71-73-8;

Drug name : Pentothal;

Chemical formula : C11H17N2O2S.Na;

ChEBI ID : CHEBI:9561;

Details

Origin ID

C66599;

UMLS CUI

C0936073;

Automatic exact mappings (from CISMeF team)
- thiopental [MeSH Descriptor]
Currated CISMeF NLP mapping
- Sodium thiopental [ICHI extension code]
- Sodium thiopentone [ICD-11 Extension code]
- Thiopental Sodium [MeSH concept]
- Thiopental sodium [Substance BNPC]
- Thiopental sodium [ICD-11 Extension code]
- Thiopental sodium [SMS substance]
- Thiopental sodium (substance) [SNOMED CT concept]
- thiopental sodium [SNOMED Notion]
See also inter- (CISMeF)
- Thiopental sodium (product) [Inactive SNOMED CT concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
Validated automatic mappings to NTBT
- thiopental [MeSH Descriptor]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_free_acid_or_base_form
- Thiopental [NCIt concept]
is_salt_form_of
- Thiopental [NCIt concept]

Keyword's position in hierarchy(ies) :

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