Ampulla of Vater Signet Ring Cell Adenocarcinoma

Preferred Label : Ampulla of Vater Signet Ring Cell Adenocarcinoma;

NCIt synonyms : Ampullary Signet Ring Cell Carcinoma; Ampulla of Vater Signet-Ring Cell Carcinoma; Ampulla of Vater Signet Ring Cell Carcinoma;

NCIt definition : An adenocarcinoma arising from the ampulla of Vater. Morphologically, it is characterized by the presence of mucin-containing signet-ring cells.;

Neoplastic status : Malignant;

Details

Origin ID

C6656;

UMLS CUI

C1332249;

Automatic exact mappings (from CISMeF team)
- ampullary signet ring cell adenocarcinoma [DO Concept]
DO Cross reference
- ampullary signet ring cell adenocarcinoma [DO Concept]
Disease excludes abnormal cell
- Malignant Squamous Cell [NCIt concept]
- Malignant Stromal Cell [NCIt concept]
- Neoplastic Smooth Muscle Cell [NCIt concept]
- Neoplastic Squamous Cell [NCIt concept]
Disease may have findings
- Abdominal Pain [NCIt concept]
- Anorexia [NCIt concept]
- Jaundice [NCIt concept]
- Lower Gastrointestinal Hemorrhage [NCIt concept]
- Malaise [NCIt concept]
- Nausea [NCIt concept]
- Pruritus [NCIt concept]
- Vomiting [NCIt concept]
- Weight Loss [NCIt concept]
Has associated anatomic sites
- Ampulla of Vater [NCIt concept]
- Digestive System [NCIt concept]
- Intestine [NCIt concept]
- Small Intestine [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- ampullary signet ring cell adenocarcinoma [DO Concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Intermediate Grade Neuroendocrine Lesion [NCIt concept]
- Intestinal Metaplasia [NCIt concept]
- Low Grade Neuroendocrine Lesion [NCIt concept]
- Mixed Neoplastic Glandular and Squamous Cell Population [NCIt concept]
- Mucoid Stroma Formation [NCIt concept]
- Well Differentiated Neuroendocrine Lesion [NCIt concept]
disease_has_abnormal_cell
- Adenocarcinoma Cell [NCIt concept]
- Malignant Cell [NCIt concept]
- Malignant Epithelial Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Epithelial Cell [NCIt concept]
- Neoplastic Glandular Cell [NCIt concept]
- Signet Ring Adenocarcinoma Cell [NCIt concept]
disease_has_finding
- Carcinomatous Component Present [NCIt concept]
- Epithelial Component Present [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
disease_has_normal_cell_origin
- Epithelial Cell [NCIt concept]
- Glandular Cell [NCIt concept]
- Small Intestinal Glandular Cell [NCIt concept]
disease_has_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
- Glandular Epithelium [NCIt concept]
- Small Intestinal Mucosa [NCIt concept]
disease_has_primary_anatomic_site
- Ampulla of Vater [NCIt concept]
- Digestive System [NCIt concept]
- Small Intestine [NCIt concept]
disease_mapped_to_gene
- KRAS Gene [NCIt concept]
- SMAD4 Gene [NCIt concept]
- TP53 Gene [NCIt concept]
disease_may_have_associated_disease
- Crohn Disease [NCIt concept]
disease_may_have_cytogenetic_abnormality
- Loss of Chromosome 17p [NCIt concept]
- Loss of Chromosome 18q [NCIt concept]
- Loss of Chromosome 5q [NCIt concept]
disease_may_have_molecular_abnormality
- CTNNB1 Gene Mutation [NCIt concept]
- KRAS Gene Mutation [NCIt concept]
- Loss of E-cadherin Expression [NCIt concept]
- Microsatellite Instability [NCIt concept]
- SMAD4 Gene Inactivation [NCIt concept]
- TP53 Gene Inactivation [NCIt concept]

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