Protokylol Hydrochloride

Preferred Label : Protokylol Hydrochloride;

NCIt definition : The hydrochloride salt form of protokylol, a derivative of the beta-adrenergic receptor agonist isoproterenol with bronchodilator activity. Protokylol binds to beta-2 adrenergic receptors in bronchial smooth muscle, thereby activating intracellular adenyl cyclase, an enzyme that catalyzes the conversion of adenosine triphosphate (ATP) to cyclic-3',5'-adenosine monophosphate (cAMP). Increased cAMP levels cause relaxation of bronchial smooth muscle, relieve bronchospasms, improve mucociliary clearance and inhibit the release of mediators of immediate hypersensitivity from cells, especially from mast cells.;

UNII : 7U7O8Q48IO;

InChIKey : LOVXREQUMZKFCM-UHFFFAOYSA-N;

CAS number : 136-69-6;

Chemical formula : C18H21NO5.HCl;

Details

Origin ID

C66496;

UMLS CUI

C0770472;

Currated CISMeF NLP mapping
- Protokylol hydrochloride (substance) [SNOMED CT concept]
- protokylol hydrochloride [Substance BNPC]
- protokylol hydrochloride [MeSH concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Protokylol hydrochloride (substance) [SNOMED CT concept]
- protokylol hydrochloride [Substance BNPC]
- protokylol hydrochloride [MeSH concept]
Validated automatic mappings to NTBT
- Protokylol (substance) [SNOMED CT concept]
- protokylol [SNOMED Notion]
- protokylol [MeSH Supplementary Concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_free_acid_or_base_form
- Protokylol [NCIt concept]
is_salt_form_of
- Protokylol [NCIt concept]

Keyword's position in hierarchy(ies) :

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