Pirbenicillin - CISMeF

Preferred Label : Pirbenicillin;

NCIt definition : A semisynthetic penicillin with antibacterial activity. Pirbenicillin binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This interrupts bacterial cell wall synthesis and results in the weakening of the bacterial cell wall and causes cell lysis.;

UNII : 8ARY01XRYU;

InChIKey : WRFCGBVLTRJBKN-QSNWEANLSA-N;

CAS number : 55975-92-3;

Chemical formula : C24H26N6O5S;

Details

Origin ID

C66414;

UMLS CUI

C0071128;

Currated CISMeF NLP mapping
- Pirbenicillin [SMS substance]
- pirbenicillin [MeSH concept]
- pirbenicillin [MeSH Supplementary Concept]
Semantic type(s)
- Antibiotic [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- pirbenicillin [MeSH concept]
- pirbenicillin [MeSH Supplementary Concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_salt_form
- Pirbenicillin Sodium [NCIt concept]
is_free_acid_or_base_form_of
- Pirbenicillin Sodium [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients