Pemirolast - CISMeF

Preferred Label : Pemirolast;

NCIt synonyms : 4H-Pyrido(1,2-a)Pyrimidin-4-One, 9-Methyl-3-(1H-Tetrazol-5-yl)-;

NCIt definition : A pyrimidinone derivative with anti-allergic activity. Pemirolast blocks the antigen-mediated calcium ion influx into mast cells. This prevents mast cell degranulation, resulting in mast cell stabilization and inhibition of the release of inflammatory mediators, such as histamine and leukotrienes, which are involved in the allergic process. Pemirolast also prevents inflammatory mediator release from eosinophils.;

UNII : 2C09NV773M;

InChIKey : HIANJWSAHKJQTH-UHFFFAOYSA-N;

CAS number : 69372-19-6;

Chemical formula : C10H8N6O;

Details

Origin ID

C66334;

UMLS CUI

C0053881;

Automatic exact mappings (from CISMeF team)
- Pemirolast [ICD-11 Extension code]
Currated CISMeF NLP mapping
- Pemirolast (substance) [SNOMED CT concept]
- pemirolast [MeSH concept]
- pemirolast [MeSH Supplementary Concept]
See also inter- (CISMeF)
- Product containing pemirolast (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Pemirolast (substance) [SNOMED CT concept]
- Product containing pemirolast (medicinal product) [SNOMED CT concept]
- pemirolast [MeSH concept]
- pemirolast [MeSH Supplementary Concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_salt_form
- Pemirolast Potassium [NCIt concept]
is_free_acid_or_base_form_of
- Pemirolast Potassium [NCIt concept]

Keyword's position in hierarchy(ies) :

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