Micafungin Sodium

Preferred Label : Micafungin Sodium;

NCIt definition : The sodium salt form of micafungin, a semi-synthetic echinocandin derived from a natural product of the fungus Coleophoma empetri with antifungal activity. Micafungin, like other cyclic lipopeptides, noncompetitively inhibits the fungal specific enzyme 1,3-beta-D-glucan synthase, an enzyme essential for the synthesis of the important fungal cell wall component 1,3-beta-D-glucan. By preventing the synthesis of 1,3-beta-D-glucan, the cell wall is weakened which leads to osmotic lysis and eventually fungal cell death.;

UNII : IS1UP79R56;

InChIKey : KOOAFHGJVIVFMZ-WZPXRXMFSA-M;

CAS number : 208538-73-2;

Chemical formula : C56H70N9O23S.Na;

Details

Origin ID

C66145;

UMLS CUI

C1576821;

Automatic exact mappings (from CISMeF team)
- Micafungin [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Antibiotic [UMLS semantic type]
Validated automatic mappings to NTBT
- Micafungin [MeSH Descriptor]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
has_free_acid_or_base_form
- Micafungin [NCIt concept]
is_salt_form_of
- Micafungin [NCIt concept]

Keyword's position in hierarchy(ies) :

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