Levomepromazine

Preferred Label : Levomepromazine;

NCIt synonyms : Methotrimeprazine; (-)-10-(3-(Dimethylamino)-2-methylpropyl)-2-methoxyphenothiazine;

NCIt definition : A phenothiazine and typical antipsychotic agent, with sedative/hypnotic, anxiolytic, antiemetic, analgesic and antipsychotic activities. Although the exact mechanism of action of levomepromazine is not fully known, upon administration, this agent appears to act as an antagonist for a variety of receptors in the central nervous system (CNS), including adrenergic, dopamine, histamine, cholinergic and serotonin (5-hydroxytryptamine; 5-HT) receptors. Blocking these receptors results in levomepromazine's pharmacologic effects.;

UNII : 9G0LAW7ATQ;

InChIKey : VRQVVMDWGGWHTJ-CQSZACIVSA-N;

CAS number : 60-99-1;

Drug name : Levoprome; Neozine; Nirvan; Nozinan;

Molecule name : Arc-VI-C-5; Bayer 1213;

Chemical formula : C19H24N2OS;

ChEBI ID : CHEBI:6838;

Details

Origin ID

C66118;

UMLS CUI

C0025678;

Currated CISMeF NLP mapping
- Levomepromazine [ICD-11 Extension code]
- Levomepromazine [ICHI extension code]
- Levomepromazine [SMS substance]
- Levomepromazine [LOINC component]
- Levomepromazine (substance) [SNOMED CT concept]
- Methotrimeprazine [LOINC component]
- Methotrimeprazine [ICD-11 Extension code]
- Methotrimeprazine [ICHI extension code]
- methotrimeprazine [Substance BNPC]
- methotrimeprazine [MeSH Descriptor]
- methotrimeprazine [MeSH concept]
- methotrimeprazine [SNOMED Notion]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Levomepromazine [ICD-11 Extension code]
- Levomepromazine [LOINC component]
- Levomepromazine (substance) [SNOMED CT concept]
- Methotrimeprazine [LOINC component]
- Methotrimeprazine [ICD-11 Extension code]
- Product containing levomepromazine (medicinal product) [SNOMED CT concept]
- levomepromazine [ATC Code]
- methotrimeprazine [Substance BNPC]
- methotrimeprazine [MeSH Descriptor]
- methotrimeprazine [MeSH concept]
- methotrimeprazine [SNOMED Notion]
Validated automatic mappings to BTNT
- Levomepromazine hydrochloride (substance) [SNOMED CT concept]
- levomepromazine [ATC Code]
- methotrimeprazine hydrochloride [SNOMED Notion]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_salt_form
- Levomepromazine Hydrochloride [NCIt concept]
- Levomepromazine Maleate [NCIt concept]
is_free_acid_or_base_form_of
- Levomepromazine Hydrochloride [NCIt concept]
- Levomepromazine Maleate [NCIt concept]

Keyword's position in hierarchy(ies) :

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