Methohexital Sodium

Preferred Label : Methohexital Sodium;

NCIt related terms : Brevital;

NCIt definition : The sodium salt of methohexital, a rapid, short-acting barbituric acid derivative, with anesthetic activity. Methohexital binds to the chloride ionophore site of the gamma-aminobutyric acid (GABA)-A/chloride ionophore receptor complex, thereby enhancing the inhibitory actions of GABA-A in the brain. This leads to synaptic inhibition, decreased neuronal excitability and induction of anesthesia. In addition, this agent decreases glutamate (Glu) responses.;

UNII : 60200PNZ7Q;

InChIKey : KDXZREBVGAGZHS-UHFFFAOYSA-M;

CAS number : 309-36-4;

Drug name : Brevital;

Chemical formula : C14H17N2O3.Na;

ChEBI ID : CHEBI:6834;

Details

Origin ID

C66117;

UMLS CUI

C0304448;

Currated CISMeF NLP mapping
- Methohexital Sodium [MeSH concept]
- Methohexital sodium [Substance BNPC]
- Methohexital sodium (substance) [SNOMED CT concept]
- methohexital sodium [SNOMED Notion]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Methohexital Sodium [MeSH concept]
- Methohexital sodium [Substance BNPC]
- Methohexital sodium (substance) [SNOMED CT concept]
- methohexital sodium [SNOMED Notion]
Validated automatic mappings to NTBT
- methohexital [MeSH Descriptor]
concept_is_in_subset
- CPTAC Baseline Medical Forms Terminology [NCIt concept]
- CPTAC Surgery-Anesthesia Form [NCIt concept]
- CPTAC Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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