Methohexital - CISMeF

Preferred Label : Methohexital;

NCIt synonyms : 2,4,6(1H,3H,5H)-Pyrimidinetrione, 1-methyl-5-(1-methyl-2-pentynyl)-5-(2-propenyl)-, ( -)-; ( -)-5-Allyl-1-methyl-5-(1-methyl-2-pentynyl)barbituric Acid;

NCIt definition : A rapid, short-acting barbituric acid derivative, with anesthetic activity. Methohexital binds to the chloride ionophore site of the gamma-aminobutyric acid (GABA)-A/chloride ionophore receptor complex, thereby enhancing the inhibitory actions of GABA-A in the brain. This leads to synaptic inhibition, decreased neuronal excitability, and induction of anesthesia. In addition, this agent decreases glutamate (Glu) responses.;

UNII : E5B8ND5IPE;

InChIKey : NZXKDOXHBHYTKP-UHFFFAOYSA-N;

CAS number : 151-83-7; 18652-93-2;

Chemical formula : C14H18N2O3;

ChEBI ID : CHEBI:102216;

Details

Origin ID

C66116;

UMLS CUI

C0025668;

Automatic exact mappings (from CISMeF team)
- Methohexital [ICHI extension code]
Currated CISMeF NLP mapping
- Methohexital [Substance BNPC]
- Methohexital [ICD-11 Extension code]
- Methohexital [LOINC component]
- Methohexital (substance) [SNOMED CT concept]
- methohexital [MeSH Descriptor]
- methohexital [MeSH concept]
- methohexital [SNOMED Notion]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Methohexital [Substance BNPC]
- Methohexital [ICD-11 Extension code]
- Methohexital [LOINC component]
- Methohexital (substance) [SNOMED CT concept]
- Product containing methohexital (medicinal product) [SNOMED CT concept]
- methohexital [ATC Code]
- methohexital [ATC Code]
- methohexital [MeSH Descriptor]
- methohexital [SNOMED Notion]
- methohexital [MeSH concept]
Validated automatic mappings to BTNT
- methohexital [ATC Code]
- methohexital [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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