Mephenytoin - CISMeF

Preferred Label : Mephenytoin;

NCIt synonyms : 3-Ethylnirvanol; 2,4-Imidazolidinedione, 5-ethyl-3-methyl-5-phenyl-; 3-Methyl-5,5-phenylethylhydantoin;

NCIt definition : A heterocyclic organic compound with anticonvulsant property. Although the mechanism of action is not well established, mephenytoin potentially promotes sodium efflux from neurons in motor cortex, and stabilizes the threshold against hyperexcitability caused by excessive stimulation. Thus this agent reduces the membrane sodium gradient and prevents cortical seizure signal spreading. It may cause blood dyscrasias, therefore, this agent was only used after other less toxic anticonvulsants had failed.;

UNII : R420KW629U;

InChIKey : GMHKMTDVRCWUDX-UHFFFAOYSA-N;

CAS number : 50-12-4;

Chemical formula : C12H14N2O2;

NSC code : 34652;

Details

Origin ID

C66091;

UMLS CUI

C0025381;

See also inter- (CISMeF)
- Product containing mephenytoin (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Mephenytoin [ICD-11 Extension code]
- Mephenytoin [LOINC component]
- Mephenytoin (substance) [SNOMED CT concept]
- Product containing mephenytoin (medicinal product) [SNOMED CT concept]
- mephenytoin [ATC Code]
- mephenytoin [Substance BNPC]
- mephenytoin [MeSH concept]
- mephenytoin [MeSH Descriptor]
- mephenytoin [SNOMED Notion]
Validated automatic mappings to BTNT
- mephenytoin [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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