Linogliride - CISMeF

Preferred Label : Linogliride;

NCIt synonyms : N-(1-Methyl-2-pyrrolidinylidene)-N'-phenyl-4-morpholinecarboxamidine;

NCIt definition : A guanidine-based insulin secratogogue and structural analogue of pirogliride with hypoglycemic activity. Linogliride blocks ATP-sensitive potassium channels on the membranes of pancreatic beta cells which stimulates the secretion of insulin and improves glucose tolerance. This agent is associated with CNS toxicity.;

UNII : 7E521JYJ4X;

InChIKey : OPPLDIXFHYTSSR-YQFKSOGVSA-N;

CAS number : 75358-37-1;

Chemical formula : C16H22N4O;

Details

Origin ID

C66015;

UMLS CUI

C0065013;

Currated CISMeF NLP mapping
- linogliride [MeSH concept]
- linogliride [MeSH Supplementary Concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- linogliride [MeSH concept]
- linogliride [MeSH Supplementary Concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_salt_form
- Linogliride Fumarate [NCIt concept]
is_free_acid_or_base_form_of
- Linogliride Fumarate [NCIt concept]

Keyword's position in hierarchy(ies) :

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