Isoproterenol Sulfate

Preferred Label : Isoproterenol Sulfate;

NCIt definition : The sulfate salt form of isoproterenol, a beta-adrenergic receptor agonist with bronchodilator activity. Isoproterenol binds to beta-2 adrenergic receptors in bronchial smooth muscle, thereby activating intracellular adenyl cyclase, an enzyme that catalyzes the conversion of adenosine triphosphate (ATP) to cyclic-3',5'-adenosine monophosphate (cAMP). Increased cAMP levels cause relaxation of bronchial smooth muscle, relieve bronchospasms, improve mucociliary clearance and inhibit the release of mediators of immediate hypersensitivity from cells, especially from mast cells.;

UNII : 925FX3X776;

InChIKey : CUQPTVCVZLUXJB-UHFFFAOYSA-N;

CAS number : 6078-56-4;

Chemical formula : 2C11H17NO3.2H2O.H2SO4;

Details

Origin ID

C65983;

UMLS CUI

C0282211;

Automatic exact mappings (from CISMeF team)
- isoproterenol [MeSH Descriptor]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Isoprenaline sulfate (substance) [SNOMED CT concept]
- isoprenaline sulphate [Substance BNPC]
- isoproterenol sulfate [MeSH concept]
- isoproterenol sulfate [SNOMED Notion]
Validated automatic mappings to NTBT
- isoproterenol [MeSH Descriptor]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_free_acid_or_base_form
- Isoproterenol [NCIt concept]
is_salt_form_of
- Isoproterenol [NCIt concept]

Keyword's position in hierarchy(ies) :

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