NCIt definition : A beta-adrenergic receptor agonist with bronchodilator activity. Isoetharine selectively
binds to beta-2 adrenergic receptors in bronchial smooth muscle, thereby activating
intracellular adenyl cyclase, an enzyme that catalyzes the conversion of adenosine
triphosphate (ATP) to cyclic-3',5'-adenosine monophosphate (cAMP). Increased cAMP
levels cause relaxation of bronchial smooth muscle, relieve bronchospasms, improve
mucociliary clearance and reduce mediator substance release from inflammatory cells,
especially from mast cells.;