Imidaprilat - CISMeF

Preferred Label : Imidaprilat;

NCIt definition : An angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. Imidaprilat competitively binds to and inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II. This prevents the potent vasoconstrictive actions of angiotensin II and results in vasodilation. Imidaprilat also decreases angiotensin II-induced aldosterone secretion by the adrenal cortex, which leads to an increase in sodium excretion and subsequently increases water outflow.;

UNII : WUU07Y30IA;

CAS number : 89371-44-8;

Chemical formula : C18H23N3O6;

Details

Origin ID

C65893;

UMLS CUI

C0246977;

Currated CISMeF NLP mapping
- imidaprilat [MeSH concept]
- imidaprilat [MeSH Supplementary Concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- imidaprilat [MeSH Supplementary Concept]
- imidaprilat [MeSH concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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