Hetacillin Potassium

Preferred Label : Hetacillin Potassium;

NCIt definition : The potassium salt of hetacillin, a semi-synthetic penicillin antibiotic with bactericidal activity. Hetacillin is a prodrug that is converted to ampicillin via esterases. Ampicillin binds to and inactivated penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall, thereby preventing the cross-linkage of peptidoglycans, which are critical components of the bacterial cell wall. This leads to an interruption of the bacterial cell wall and causes bacterial cell lysis.;

UNII : 95PFX5932Y;

InChIKey : QRSPJBLLJXVPDD-XFAPPKAWSA-M;

CAS number : 5321-32-4;

Chemical formula : C19H22N3O4S.K;

ChEBI ID : CHEBI:34789;

Details

Origin ID

C65845;

UMLS CUI

C0812398;

Automatic exact mappings (from CISMeF team)
- hetacillin [SNOMED Notion]
Currated CISMeF NLP mapping
- Hetacillin potassium [SMS substance]
Semantic type(s)
- Antibiotic [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
Validated automatic mappings to NTBT
- Hetacillin (substance) [SNOMED CT concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_free_acid_or_base_form
- Hetacillin [NCIt concept]
is_salt_form_of
- Hetacillin [NCIt concept]

Keyword's position in hierarchy(ies) :

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