Fuzlocillin - CISMeF

Preferred Label : Fuzlocillin;

NCIt definition : A semisynthetic acylureidopenicillin with antibacterial activity. Fuzlocillin binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This interrupts bacterial cell wall synthesis and results in the weakening of the bacterial cell wall, eventually causing cell lysis.;

UNII : J6UQP7JHOT;

InChIKey : YSUBQYRZZFVMTL-YNDGFOBUSA-N;

CAS number : 66327-51-3;

Chemical formula : C25H26N6O8S;

Détails

Origin ID

C65794;

UMLS CUI

C0060856;

Currated CISMeF NLP mapping
- Fuzlocillin [SMS substance]
- furazlocillin [MeSH Supplementary Concept]
- furazlocillin [MeSH concept]
Semantic type(s)
- Antibiotic [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- furazlocillin [MeSH concept]
- furazlocillin [MeSH Supplementary Concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]

Position du mot-clé dans l'(les) arborescence(s) :

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