Fosphenytoin - CISMeF

Preferred Label : Fosphenytoin;

NCIt definition : A water-soluble phosphate ester prodrug of phenytoin, a hydantoin derivative with anticonvulsant activity. Fosphenytoin is hydrolyzed to phenytoin by phosphatases. Phenytoin exerts its effect mainly by promoting sodium efflux and stabilizes neuronal membranes in the motor cortex. This leads to a suppression of excessive neuronal firing and limits the spread of seizure activity.;

UNII : B4SF212641;

InChIKey : XWLUWCNOOVRFPX-UHFFFAOYSA-N;

CAS number : 93390-81-9;

Chemical formula : C16H15N2O6P;

Details

Origin ID

C65766;

UMLS CUI

C0244656;

Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Fosphenytoin [LOINC component]
- Fosphenytoin (substance) [SNOMED CT concept]
- Product containing fosphenytoin (medicinal product) [SNOMED CT concept]
- fosphenytoin [ATC Code]
- fosphenytoin [MeSH concept]
- fosphenytoin [MeSH Supplementary Concept]
Validated automatic mappings to BTNT
- fosphenytoin [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_salt_form
- Fosphenytoin Sodium [NCIt concept]
is_free_acid_or_base_form_of
- Fosphenytoin Sodium [NCIt concept]

Keyword's position in hierarchy(ies) :

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