" /> Febuxostat - CISMeF





Preferred Label : Febuxostat;

NCIt synonyms : 2-(3-Cyano-4-(2-methylpropoxy)phenyl)-4-methylthiazole-5-carboxylic Acid;

NCIt definition : An orally available, non-purine inhibitor of xanthine oxidase with uric acid lowering activity. Upon oral administration, febuxostat selectively and noncompetitively inhibits the activity of xanthine oxidase, an enzyme that converts oxypurines, including hypoxanthine and xanthine, into uric acid. By inhibiting xanthine oxidase, uric acid production is reduced and serum uric acid levels are lowered. Febuxostat may provide protection against acute renal failure caused by the excessive release of uric acid that occurs upon massive tumor cell lysis resulting from the treatment of some malignancies.;

UNII : 101V0R1N2E;

InChIKey : BQSJTQLCZDPROO-UHFFFAOYSA-N;

CAS number : 144060-53-7; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 144060-53-7 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Drug name : Uloric; Adenuric;

Molecule name : TMX 67;

Chemical formula : C16H16N2O3S;

ChEBI ID : CHEBI:31596;

PubMed : 16339094;

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15/05/2024


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