NCIt definition : An adrenergic agonist with vasoconstrictive activity. Etilefrine selectively binds
to and activates alpha-1-adrenergic receptors of the arteriolar and venous vasculature.
This causes smooth muscle contraction and leads to a decrease in venous pooling and
increase in blood pressure. This agent may also stimulate beta-1 adrenergic receptors,
leading to positive chronotropic and inotropic effects.;