" /> Esomeprazole Sodium - CISMeF





Preferred Label : Esomeprazole Sodium;

NCIt synonyms : 1H-Benzimidazole, 6-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2- pyridinyl)methyl]sulfinyl]-, Sodium Salt (1:1);

NCIt definition : The sodium salt of the S-isomer of omeprazole, with gastric proton pump inhibitor activity. In the acidic compartment of parietal cells, esomeprazole is protonated and converted into the active achiral sulfenamide; the active sulfenamide forms one or more covalent disulfide bonds with the proton pump hydrogen-potassium adenosine triphosphatase (H /K ATPase), thereby inhibiting its activity and the parietal cell secretion of H ions into the gastric lumen, the final step in gastric acid production. H /K ATPase is an integral membrane protein of the gastric parietal cell.;

UNII : L2C9GWQ43H;

InChIKey : RYXPMWYHEBGTRV-JIDHJSLPSA-N;

CAS number : 161796-78-7;

Chemical formula : C17H18N3O3S.Na;

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08/05/2025


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