Preferred Label : Eprodisate Disodium;
NCIt synonyms : 1,3-Propanedisulfonic Acid, Disodium Salt;
NCIt definition : The orally available disodium salt form of eprodisate, a negatively charged sulfonated
inhibitor of fibrillogenesis, that can be used in the treatment of amyloid A (AA)
amyloidosis. Upon administration, eprodisate competitively binds to the glycosaminoglycan
binding sites on serum amyloid A (SAA), which inhibits the formation of the glycosaminoglycan-amyloid
fibril aggregate. This prevents the formation of amyloid deposits in certain organs,
especially the kidneys, in AA amyloidosis.;
UNII : 5X0D9H16IU;
InChIKey : DKGJFKPIUSHDIT-UHFFFAOYSA-L;
CAS number : 36589-58-9;
Molecule name : NC 503;
Chemical formula : C3H6O6S2.2Na;
Origin ID : C65520;
UMLS CUI : C1880542;
Semantic type(s)
- concept_is_in_subset
- has_target
