Eprodisate Disodium

Preferred Label : Eprodisate Disodium;

NCIt synonyms : 1,3-Propanedisulfonic Acid, Disodium Salt;

NCIt definition : The orally available disodium salt form of eprodisate, a negatively charged sulfonated inhibitor of fibrillogenesis, that can be used in the treatment of amyloid A (AA) amyloidosis. Upon administration, eprodisate competitively binds to the glycosaminoglycan binding sites on serum amyloid A (SAA), which inhibits the formation of the glycosaminoglycan-amyloid fibril aggregate. This prevents the formation of amyloid deposits in certain organs, especially the kidneys, in AA amyloidosis.;

UNII : 5X0D9H16IU;

InChIKey : DKGJFKPIUSHDIT-UHFFFAOYSA-L;

CAS number : 36589-58-9;

Molecule name : NC 503;

Chemical formula : C3H6O6S2.2Na;

Details

Origin ID

C65520;

UMLS CUI

C1880542;

Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
has_target
- Serum Amyloid A [NCIt concept]

Keyword's position in hierarchy(ies) :

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