Preferred Label : Disuprazole;
NCIt definition : A 4-ethylthio-3-methylpyridine analogue of omeprazole with no substituent on the benzimidazole
ring, with selective and irreversible proton pump inhibitor activity. Once converted
to its active sulfenamide form, disuprazole forms a stable disulfide bond with the
sulfhydryl group of the hydrogen-potassium (H /K ) ATPase found on the secretory surface
of parietal cells, thereby inhibiting the final transport of hydrogen ions (via exchange
with potassium ions) into the gastric lumen and suppressing gastric acid secretion.;
UNII : V81J4OO2OT;
InChIKey : YWQUFKJVMWHDSN-UHFFFAOYSA-N;
CAS number : 99499-40-8;
Chemical formula : C16H17N3OS2;
Origin ID : C65441;
UMLS CUI : C1880366;
Semantic type(s)
- concept_is_in_subset
