Preferred Label : Dioxifedrine;
NCIt definition : A beta-2 -adrenergic agonist with bronchodilator activity. Dioxifedrine selectively
binds to and activates beta-2 adrenergic receptors in bronchiolar smooth muscle, thereby
causing stimulation of adenyl cyclase, the enzyme that catalyzes the conversion of
adenosine triphosphate (ATP) to cyclic-3',5'-adenosine monophosphate (cAMP). Increased
intracellular cAMP levels cause relaxation of bronchial smooth muscle. This increases
air flow and prevents bronchospasms and may eventually lead to an improvement of airway
function.;
UNII : CF48QOH154;
InChIKey : DDBFLXGTCAVAFD-UHFFFAOYSA-N;
CAS number : 10329-60-9;
Chemical formula : C10H15NO3;
Origin ID : C65417;
UMLS CUI : C1880341;
Currated CISMeF NLP mapping
Semantic type(s)
concept_is_in_subset